Paul Duhem was born in Blandain, Belgium, 1919. He left school at age 14 and worked as a farmhand. During the Second World War he went to work in Germany. Upon return in his country, he was arrested for collaboration with the Germans. Because of his mental disabilities, he was transferred from prison to a psychiatric hospital before being employed as a labourer in farms in the region.
In 1977 he was admitted to a home where he did horticulture. Twelve years later, at the age of 70, Paul Duhem started to draw within the framework of a workshop until his death in 1999.